* Note: While this may come off as a post against the CR-Z, do not take it that way
I think what needs to be considered, first and foremost, is how much money you're spending, and what else you can get for that same amount of cash. Give or take, a CR-Z is going to run you between $20-22K. To be frank, there are a wide variety of vehicles that can be had for that kind of money, several of which I think should be seriously considered before settling only on the CR-Z. Things like...
* MKVI VW Golf 3-Door
Pro: Increased practicality, everyday performance, reasonable pricing
Con: Poor fuel economy, typical VW worries, insane insurance rates
* 2012 Ford Focus SE Performance Pack
Pro: European design and performance, 38 MPG, Ford Sync
Con: Expensive, limited availability, its "only a Focus."
* 2012 Fiat 500 Sport
Pro: Arguably more "unique" than the CR-Z, ladies love the shape, as close as you're going to get to an Alfa right now
Con: Its Italian, good luck finding a dealer, as close as you're going to get to an Alfa right now
* 2012 Scion iQ
Pro: Will probably be strangest vehicle sold in the US this year, when we say "maximizing the space you use" we mean "maximizing the space you use," fuel economy should be up there.
Con: This thing is seriously small, a little playskool, and would likely be classified as "cute"
Of all of those cars there, I would probably look closest at the Focus and the 500. Both are going to be difficult to come by, however, so the greatest of luck to you in that regard.
Everything else in mind, I still believe the CR-Z is a fantastic little car, Honda fanatics be damned. Sure, the car could have been lighter, it could have been a little more focused, and in the end could have been a little more green... But in the end, they stuck to a pretty straight line in the design department inside and out, and for me, it paid off. The interior alone is a place that I would love to be every day, plenty of open space with nicely designed pieces that are attractive to the eye and soft to the touch. The seats are fantastic, the driving position is great.
I really recommend shopping around, but settling on the CR-Z is still a wonderful option.