I've gone through a few tunes here and many of them don't work very well with comfort tyres if they've been tuned for very soft rubber.
Unmanageable understeer that suddenly turns into oversteer tends to happen
Yep, because alot of tuners on here either don't use comfort tyres or tune offline.
Alot of "grippy" rubber is used that can mask deficiences in the setup, these become acutely prominant when you take away the grip (given by the sticky rubber) and are left with the mechanical grip and (normally "lack of") balance (because it was tuned offline and people are using it online) that the suspension / lsd has.
You don't mention what kind of PP range and car(s) you're neeeding this for..??
When you have a half decent setup it's quite suprising how much grip and balance you can get from comfort softs or sports hards up to 500-550pp when online racing.
The car(s) being used can also have a big impact too, obviously a car that has natural balance and grip is going to be alot different to something that is like trying to wrestle a wild animal on crack.
It's hard to give out specific advice without knowing PP range, type of cars, tracks and race distance etc etc.
Shorter races you can "over tune" the car to help heat up tyres quickly, whereas longer races you'll need to balance grip and tyre wear, so tyres will take a little while longer to heat up sometimes, and you'll have to be less aggressive with the setup and driving.
On some tracks, "normal" driving will be suffcient to heat the tyes, other tracks you need to help get heat into them - but you gotta get those tyres up to operating temperatue (preferably - fr and rr at the same time / speed) as they provide little grip (if using a highish pp) and you don't want to be wasting/loosing grip if the tyres aren't heating up enough.
So driving style and steering sensitivty can also play an important part also - a smooth style might not heat them up enough, an aggressive style will wear them out too quickly.
The only thing that works for all is basic balance in your setup - there's so many different variables to consider, wthout knowing more it's almost impossible to give any kind of specific figures for any part of the setup.
Getting balance should be the same for all, whether it's a low pp road car on comforts or a Le Mans 650-700pp racecar on racing softs.
Alot of guys will setup their cars on lesser tyres than whatthey need to feel the balance, then put he correct (stickier) tyres and also aero on after.
A good balanced setup should be able to handle tyre and power changes without any major changes to the setup itself - but again, there's so many different variables it's hard to be specific..