There are many Skylines I like.
The Amuse Carbonara was hopeless in GT4. But now it's very, very good.
Both Blitz's are horrible in this game.
The two Mine's Skylines are among my absolute favourites. The '06 is a superb, superb all-rounder. But I love the '00 Skyline.
I hated it previously. I loved it after my All Tuners Tested chapter. It is the fastest tuner in the game in a straight line bar none. The fastest tuner in the game bar none, honest...check the reviews thread I have if you don't believe it. But I had so, so many battles with it in GT4 that it's a rival to me as well. A friendly one though.
The 400R is very weak. But the R-Tune and S-Tune Skylines are both straight line cruisers like nothing else around. They're very good too.
The GT-R LM is something I haven't driven in a very long time, but I love it solely for the insanity of its looks.
The normal Gran Turismo Skyline GT-R is pretty fast. And you have to love the Pace Car. You just do.
I often believe, in terms of the road Skylines, that the originals are the best - the '89 R32, the '95 R33 and the '99 R34. They're my favourites. Of course there's also the V-spec models that improve everything, but I prefer the original, crisp model. Even if it is slower, and even then, it's not like they are slow...right?
The MNP models and the N1 models are very very cool though.
The R31 GTS-R is one of my absolute favourite Nissans around. It looks pretty good and has good speed for its class. I wouldn't mind living with one.
But I hate, hate, hate the GTS R32s. They are just scams really. I don't wanna say too much else though, because I'm planning something else with them elsewhere.
I really love the pre GT-R gen ones though. I always rather liked the S54A for whatever reason, but my absolute top of the pile Nissan and Skyline in the game, of all, is the KPGC110. What style that thing has. So much in fact, I own three of the beauties. Two are tunes, one is particularly superb I find. No shameless plugging here whatsoever. But really it's a winner for me no matter what state it's in. The KPGC110 is the top of my pile.
That said, I quite like me a KPGC10 as well. And the BLRA-3 is a hilarious one solely because the price is so vastly inflated that it might as well be the most pointless car in the entire game.
The R34 TC is a very good drive from what I've seen in the past.