Tried another disc of the same game and got the same errorIt usually means the disc is too dirty/scratched/damaged to be read and copied.
NR2003, I made a copy of it to save the original disc (Which goes for up to 100 dollars on eBay), I got it working after downloading a version of it online, I guess my expensive disc is now uselessWhat game?
If you are copying the contents of the Disc to the Hard Drive, and then installing from the hard drive it might not work (since installers look for files held in D: or E: drives)