In Pokemon, there’s the Master Ball, which catches anything without fail. Also, there’s Mewtwo, especially in games where it can mega-evolve. Something similar applies to Rayquaza. Arceus is also pretty nuts, basically being the closest thing Pokemon has to YHVH.
Then in Ace Combat 5 and Ace Combat Zero, I recall that the ADF-01 Falken being absurdly powerful, with its Tactical Laser System (TLS). Its prototype, the ADFX-01 Morgan, has these crazy burst missiles, too.
Finally, in Gran Turismo, there’s the Dodge SRT Tomahawk X Vision Gran Turismo. Do I need to explain this one?