Just in case you don't know (but maybe do)...
If you haven't installed Content Manager, the regular interface for AC will no longer finish loading after you've reached a certain number of mods, or the amount of memory to load them exceeds what the interface can manage. When I see a post that someone can no longer open AC after installing a lot of mods, this is almost always the problem.
The solution to the problem, Content Manager can manage an "infinite" number of mods, and it loads much faster. However, that's one of the minor benefits, as it's packed with numerous other features that go way beyond AC's "vanilla" interface.
For anyone that still hasn't installed Content Manager...
Content Manager Download Site
I know most of the members on this forum may see a post here recommending to install Content Manager to be a little ridiculous, but you'd be surprised how many people either don't know about it, or aren't using it for some reason, usually because they've been misinformed or made the wrong assumptions about it.