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If you rewrite your genetic code so that you never age, it might be possible to rewrite it so that damage doesn't accumulate... you simply grow new tissues continuously. Of course... tissues that never stop growing and renewing themselves are often referred to as cancerous...
Even getting past that point, what would really be problematic is the accumulation of DNA coding errors over such long spans of time. You would probably need follow-up treatment every few decades to repair your genes.
Even getting past that point, what would really be problematic is the accumulation of DNA coding errors over such long spans of time. You would probably need follow-up treatment every few decades to repair your genes.