Danoff
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- Mile High City
I wanted to be done with it asap but I don't mind waiting longer, because it extends immunity more into fall/winter season.
I know, everyone wants it in the rear view mirror. But it's not binary. Based on the studies I dug up for Pfizer, your immunity grows over time from the first dose, really starting to be noticeable after 2 weeks. After 3 weeks your immunity from the 1st dose is substantial. Not as good as 2-doses, but better than, for example, a typical flu vaccine. 1-dose of Pfizer might actually rival J&J effectivity. I'm not sure on that one but it wouldn't surprise me. The 2nd dose is not really for the purpose of boosting short-term immunity, it's to make sure that immunity is retained for a decent period into the future. If you made it to 21 days after the 1st dose, your immunity statistics are respectable. To give you a feel for it, look at fig. 2 here.
Immunity from the 2nd dose can be expected to be noticed in that chart at about 7 days after the 2nd dose (which is 21 days in that study), in other words, at about 28 days the 2nd dose is having an effect. So check how the slope of the curve is not really changing that much going into and coming out of the 28 day mark or thereafter. There's no big boost in immunity starting at 28 days or starting after.
Anyway, the immunity you get by 21 days is the cake, at least in the short term - maybe not the long term. The 2nd dose is the icing.
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