On the need for booster doses...
Israel's Health Ministry has released some data on waning Pfizer vaccine protection from infection and transmission. Down to 39% overall against Delta is the main figure being reported, which is notably lower than the 65% or so seen in the UK. John Campbell's video yesterday has a breakdown of it by when people were vaccinated: those vaccinated in January, 16%; February, 44%; March, 67%; April, 75% (taken from this
news article he links to. I had a quick look for the report but couldn't find it - perhaps not available in english yet).
Protection against serious disease remains high at 86% (for those vaccinated in January).
(segment is ~7 minutes from 2:20)
One thing John doesn't talk about in that video but occurred to me was this: clearly when comparing to the UK and pondering on what it means for us, we'd have to consider the gap between doses. Particularly whether an 8 to 12 week gap will give longer lasting protection than the 3 week gap used in Israel, the US, and most of Europe. Studies have shown increased immune response after a longer gap (
example) and, although it's too soon to know, we could reasonably hope for longevity to be improved also.
His video today has further detail on the findings (handily also given in the description), and he goes on to speculate about the gap between doses. But what he misses is that, mainly because of the larger gap, people in the UK have had far less time since their second dose, and therefore comparison shouldn't be to the overall %s coming out of Israel and perhaps not even the latest month for which figures are given (i.e. those vaccinated in Israel in April could possibly be compared to those in the UK who had their second dose in April, but otherwise the data is incomparable). It will be at least 3 months before we have similar data for longevity in the UK, and even then it will be limited to mostly those aged over 65. Otherwise, his points regarding the implications for the US are valid, and presumably apply to most of Europe as well.
On cases decreasing in the UK...
Predictions for breaking 100,000 cases/day anyone? I'll say next Friday 🙁
Thankfully, that didn't happen. 'Only' 36k UK cases (England 33k) reported yesterday, and 32k (England 29k) today, continuing a downward trend from the peak last Saturday of 55k (England 51k). Sort of. We know that reports are usually lower on Monday/Tuesday reflecting reduced testing at weekends. Allowing for that, what's left is a clearer downward trend - but much shorter, only a few days long. Overall it's just as reasonable to see this week as a plateau at about 40k, albeit considerably lower than that peak.
I'd be quite surprised if we don't have a pulse of cases stemming from Silverstone. Is it a little odd that we haven't started to see it already? It was 140k people vs the 60k at Wembley the weekend before. Dunno - perhaps attendance at the events themselves isn't as much of a problem as the number of people getting together to watch on telly.
Dr Kit Yates, in yesterday's indie_SAGE presentation, came up with a few reasons beyond the list
@Touring Mars gave a couple of days ago, but I think most of the extras are a bit of a reach - particularly the notion that people are not bothering to get tested. I'm sure that happens, but there isn't any solid reason to suspect there's been a significant change in the number, although testing is down slightly (~5%). He also mentioned people exercising caution, which of course I agree has an effect.
Anyway, as a drinking game - every time he says "if it's genuine" about the fall!
(segment is ~5 minutes from 2:31)
I'd say - with the benefit of two days more data confirming it - the fall is genuine, and it's certainly very different to where we'd be had the previous upward trend continued - fewer than half the number of cases as were expected. But this weekend we've got the real test of restrictions being removed, with nightclubs, festivals, facesucking, etc, all going ahead unrestrained.
(UK dashboard hasn't been updated yet with today's figures: "Because of technical difficulties in processing England deaths data, today's update is delayed". So I may update this post when they appear.) EDITED to add today's case numbers and call it two days more data since Kit's presentation.