The world favours right-handed people.
In fact, in ages past, when perception was tempered more by superstition than reason, left-handed folk were regarded as evil - hence the etymology of the word 'sinister'.
Worse - ambisinister is the opposite of ambidextrous. As if. Yeah.
Left out of the equation, sinistral sufferers had to put up with doors, irons, scissors, screws, button configurations - all designed handily only for dextrous denizens.
Buttons and zippers on clothes are more complicated. The sexes are divided by more than just handedness.
Lefties, for instance, have to use 'opposite' torque when tightening a screw - the motion is outward 'stead of inward.
But, there are subtle ways lefties get to enforce their rights. Let's take sports; this is one of the reasons I practised left-hand bowling. The whole angle of attack is different. And 90% of the time I would be facing a right hand bat. Also - when I bowl right I attack with a counter-clockwise spin. When I bowl left it's clockwise. Feels different - best way I can explain it.
Rafael Nadal comes to mind when I think left-advantaged.
And then - closer to home - as drivers, wheel-worshippers, petrol-heads, gasoline-junkies . . . what happens when we switch from LH Drive to RH and vice-versa?
TG for the F1 GTR! An ambidextrous car that favours the ambisinistral, too - built for the aiming-eye of both lefties and rights.
Now, if we could only switch pedals with the flick of a toggle. . . .