I'm not a tuner, no, but I installed my own Haltech engine management and O2 sensor in to my GT-Four and set up the base timing and base map before it got sent off to the tuners who have a 4WD dyno. I did a lot of research in to tuning so I know what the general idea was, and I also log the data on track days and look at it on my laptop so it makes sense after a while.
So basically under high load the ECU is doing what it's been tuned for, and so as you gradually remove oxygen from the air by going up in altitude, the engine will run rich, but it's safe as rich is safe, lean is unsafe.
When I take my car up a mountain, it bangs and pops a hell of a lot more up top than it does at the bottom, due to the rich mixture. Sounds awesome