Now that some cars can, in fact, get more than one engine, I'm actually pretty excited. Not only could other engines like the one for the Aventador SV get even more chances to become compatible, but then there's the factor that some cars could get more interesting or thematically-appropriate engines. For example, that newly-added HiAce could get the LFA engine, like the Alphard did.
Personally, I still had some engines laying around that're only compatible with a single model, namely the aforementioned Aventador SV engine, but also the LS engine for the Corvette C6 ZR1, and I think the latter could be a perfect fit for other older GM vehicles, like the Pontiac GTO Judge.