Out-of-control spending, bad immigration policies, poor infrastructure, a justice system that violates Amendments 4 through 8, ingrained lobbyists, the creep towards authoritarianism, the limiting of the electoral process, corruption, and foreign policy, especially when it comes to Russia and China.
On a lower level, out of control inflation, unsustainable cost of housing, an awful government-funded healthcare plan, and social security that has my generation paying for older generations when it's likely social security won't be available for me.