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COVID-19/Coronavirus Information and Support Thread (see OP for useful links)
- Thread starter baldgye
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- UK
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Covid variant first detected in India is found in the UK
"Seventy-seven cases of B.1.617, which has potentially worrying mutations, reported in England and Scotland".
Maharashtra: double mutant found in 61% samples tested
"361 Covid-19 samples taken in Maharashtra from January to March and genome sequenced, 61% or 220 had the double mutation E484Q and L452R"
"The B.1.617 consists of two mutations in spike protein, E484Q and L452R. E484Q has the ability to slip past the immune response, and L452R too is an escape mutation. Both together are more infectious, highly transmissible, although less virulent. Akola and Amravati have shown the maximum burden. In 85.2% of the sequenced samples in Akola (27 out of 34) and in 69.3% samples in Amravati (68 out of 98), the B.1.617 lineage was found."
Not yet classed as a Variant of Concern, but seems likely it will be if it has indeed become a dominant strain
"Seventy-seven cases of B.1.617, which has potentially worrying mutations, reported in England and Scotland".
Maharashtra: double mutant found in 61% samples tested
"361 Covid-19 samples taken in Maharashtra from January to March and genome sequenced, 61% or 220 had the double mutation E484Q and L452R"
"The B.1.617 consists of two mutations in spike protein, E484Q and L452R. E484Q has the ability to slip past the immune response, and L452R too is an escape mutation. Both together are more infectious, highly transmissible, although less virulent. Akola and Amravati have shown the maximum burden. In 85.2% of the sequenced samples in Akola (27 out of 34) and in 69.3% samples in Amravati (68 out of 98), the B.1.617 lineage was found."
Not yet classed as a Variant of Concern, but seems likely it will be if it has indeed become a dominant strain
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- 2,330
- Michigan
- FuriousDemon
Meanwhile in Michigan, which is leading the country in cases right now...
https://www.mlive.com/news/grand-ra...e-school-district-to-make-masks-optional.html
https://www.mlive.com/news/grand-ra...e-school-district-to-make-masks-optional.html
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- GTP_Mars
I'm not sure about the phrase 'escape mutation' really... all mutations in the spike protein are likely to influence the efficacy of antibodies that were raised against a vaccine that has a different spike protein structure.Covid variant first detected in India is found in the UK
"Seventy-seven cases of B.1.617, which has potentially worrying mutations, reported in England and Scotland".
Maharashtra: double mutant found in 61% samples tested
"361 Covid-19 samples taken in Maharashtra from January to March and genome sequenced, 61% or 220 had the double mutation E484Q and L452R"
"The B.1.617 consists of two mutations in spike protein, E484Q and L452R. E484Q has the ability to slip past the immune response, and L452R too is an escape mutation. Both together are more infectious, highly transmissible, although less virulent. Akola and Amravati have shown the maximum burden. In 85.2% of the sequenced samples in Akola (27 out of 34) and in 69.3% samples in Amravati (68 out of 98), the B.1.617 lineage was found."
Not yet classed as a Variant of Concern, but seems likely it will be if it has indeed become a dominant strain
If it can be established that these variants are able to infect fully vaccinated people more than existing variants can, or if they lead to more vaccinated people getting ill than existing variants, then I'd say that the term 'escape mutation' would make more sense, but I reckon it is probably too early to establish that.
- 87,572
- Rule 12
- GTP_Famine
Despite there being no-one left for COVID-19 to harm (apparently), Sheffield Wednesday's 46-year old manager, Darren Moore, is now suffering from pneumonia and blood clots on his lungs after a COVID-19 diagnosis and isolation earlier in the month. Moore's a former professional footballer and international for Jamaica, and had not been in hospital for COVID, though does have asthma.
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- GTP_Mars
I hope he pulls through.
This is a classic example of what annoys me so much about people who say that COVID doesn't pose a risk to younger, otherwise fit/healthy people. Sure, it is lower risk than to older people and people with underlying health conditions, but there's still a spectrum of outcomes for otherwise healthy people, and some of them are dire. The fact is that no-one can possibly know in advance of developing COVID how susceptible to the virus they may be, even though there are clearly those who think they know, and even publicly say that, even when it is so patently and obviously BS.
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Agreed, their choice of wording might be premature. However, admittedly on scant data, it does appear able to re-infect those who have already had covid: "Incidentally, both the suspected cases of re-infection in Amravati in February had the B.1.617 lineage. Eight samples had the N440K mutation, which is associated with re-infections and has been found in Andhra Pradesh, Telangana, Karnataka and North India".
It seems reasonably clear that it has mutations that will reduce vaccine effectiveness, but no measure yet of by how much.
That this kind of thinking is becoming really quite widespread is worrying me a lot. I get that everyone wants to get some normality back, especially businesses. There's clearly selfishness involved - people saying this don't honestly think all young people won't get it; it's that they think they personally won't get it, and screw the rest. If we only had to worry about variants currently at large in the UK then we could do some macabre calculation and perhaps come out in favour of letting it rip through younger people. That might even be true of the Indian variant. It would not be true for the Brazilian variant, or a new home-grown variant with similar properties.
There's no way to persuade these people of the dangers of a possibility, which is how they see the variant threat. That the probablity of a nasty variant taking hold is directly proportional to the number of cases we tolerate appears to be beyond them.
McLaren
Premium
- 45,612
- Texas
Yep.
I don't really follow any other sport than the NBA, but there's a handful of stories from guys who caught it & report that they're still lingering from it. These are perfectly healthy, world-class athletes mainly in their 20's, their prime years of life. This article from last month breaks down the teams affected and cites a few player's experiences.
https://www.truehoop.com/p/some-nba-players-feel-covid-effects
Jayson Tatum 23 year old
Fred VanVleet 27 year old
Nassir Little 21 year old
- 2,677
- UK
- Outspacer
No idea what to make of that since the nypost has deleted the tweet! What did the guy die of? CVST with low platelet count I'm guessing? If so, one could say "no hard evidence", but there is circumstantial evidence given that combination is so incredibly rare otherwise.
ars technica had a pretty good article on it: The very common vaccine ingredient at the center of J&J, AstraZeneca drama
Of course from the numbers we've seen, even if they do cause clots, the risk is far less than not getting a vaccine at all. But as I mused on earlier, it's harder to work out the balance if it just means a short delay in getting a vaccine.
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- TexRex72
No surprise there. The article has vanished as well.
Other sources say a cause of the Cincinatti student's death hasn't been pinpointed. Possibly a heart or breathing issue, which seems like the manner by which everyone dies, so no help there, but there is no evidence of the exceedingly rare but potential clotting issue.
https://www.wlwt.com/article/corone...19-vaccine-led-to-uc-student-s-death/36147709
He could've been eaten alive by a pack of rabid deer and it still would have been a day after receiving the J&J vaccine.
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Took my first shot of Pfizer 👍
Thankfully, so far, i don't feel much side effect aside from minor fatigue and slightly numb left arm. It's only been 2 hours or so since i received it so hopefully it doesn't get much worse than that.
Thankfully, so far, i don't feel much side effect aside from minor fatigue and slightly numb left arm. It's only been 2 hours or so since i received it so hopefully it doesn't get much worse than that.
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- 4,076
- Tallinn
Daily COVID results in Estonia finally and suddenly started to go down. The two dotted lines on the left of the graph is the state of emergency held last year. This year there was no SOE and restrictions were soft, but also there was no mask or disinfectant deficit like last year.
Hospitals are working to the limit and finally there is hope that things will get better. Patients had to be relocated to other cities.
Some anti-mask, anti-restrictions and fake pandemic groups were protesting in front of the government building and in other places. Some people got caught by the police for various things but nothing serious happened.
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- 4,003
- Null Island
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- GTP_Mars
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Which will be more than a week after the India variant was detected here.
The horse has been wheeled into the city, the Trojans are all dead, and now Priam warns the bodies a huge fleet of Greek ships has been spotted crossing the Aegean...
Joey D
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- GTP_Joey
- GTP Joey
Ya I really don't understand why any country discovers something then says "well we're going to allow people to fly in for X amount of time before we shut down flights." I mean that would work if you quarantined people flying in, but I highly doubt that's happening. Also, logistically you probably couldn't keep track of everyone that needed to be quarantined.
We botched the whole travel thing in the US badly at the start of the pandemic. It took us weeks to ban flights from China and when the UK variant was discovered, we waited a few weeks before banning flights from there too.
We botched the whole travel thing in the US badly at the start of the pandemic. It took us weeks to ban flights from China and when the UK variant was discovered, we waited a few weeks before banning flights from there too.
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- TenEightyOne
- TenEightyOne
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