@RACECAR Like OZZY said, the E-11 is one of the best weapons you can get. The closest competitor is the A280C. The A280C has a higher firing rate with slightly less damage, but the E-11 has a slower firing rate with slightly higher damage. It's really a matter of personal preference. Even some of the most experienced players swear by the A280C for it's reliability.
The blaster pistols in this game are excellent. You'll have a lot of fun with the DH-17 since it's fully automatic, but remember that it has a severe damage and accuracy drop-off at long range. The SE-14C is a five-shot burst pistol, but don't let that discourage you; it's a monster at close-quarters combat. If I remember correctly, the maximum damage each bolt will deal is 20 at extreme close-range, but expect that to drop off the further away your target is. The DL-44 will receive a buff soon, as it's firing rare was nerfed. It can still deal 50 damage per shot in CQC.
With the loadouts, or "hands" as they are called in this game, you should think about which star cards will be most beneficial to you in each situation. If you're playing Walker Assault on the Rebel side, a loadout with some Ion-based weaponry (Such as the Ion Torpedo, Ion Shot, or Ion Grenade) is essential, but you'll only need them during the Y-Wing bombing runs or if you encounter an AT-ST. If you're playing Blast, a Jump Pack, Scan Pulse, or a Scout Pistol (Two shots; make them count) can really help you. Keep in mind that primary weapons
Now, let's talk about Charge Cards, since I was confused by them initially. Charge Cards are the ones kept in the top, center of your "hand." You can only use these cards if you have enough charges for them. Charges can either be purchased or found on the battlefield as glowing blue spark icons. Charge cards can be activated by pressing Triangle.
If you're using Explosive Shot or Ion Shot, your charge won't be used up as long as you don't press the fire button. Explosive shot will give your primary weapon a damage boost, but you will overheat faster. Ion Shot will allow you to deal more damage to droids, vehicles, turrets, and turbolasers. Scan Pulse will reveal the location of all enemies nearby for an extremely brief time in four pulses.
Your pulses do not appear for your teammates. Personal Shield will prevent you from being killed by blasters or grenades, but you can be easily killed by the Scatter Gun or Cycler Rifle. Cooling cell will prevent your primary weapon from overheating for a short time. Useful for attacking a Hero or Villain. Focus Fire will temporarily give your weapon increased accuracy for attacking long-range targets. Focus Fire and the CA-87 shotgun are a deadly combination. Adrenaline Stim is locked to the Outer Rim DLC, and the Disruption card is locked to the Bespin DLC as far as I know.